Breztri Aerosphere Caution For Usage

Instructions for use: To ensure proper administration of the medicinal product, the patient should be shown how to use the inhaler correctly by a physician or other healthcare professional, who should also regularly check the adequacy of the patient's inhalation technique. The patient should be advised to read the Package Leaflet carefully and follow the instructions for use as given in the leaflet.
Note: It is important to instruct the patients to: Not use the inhaler if the drying agent, which is inside the foil pouch, has leaked out of its packet. For best results the inhaler should be at room temperature before use.
Prime the inhaler by shaking it and actuating into the air four times before first use or two times when the inhaler has not been used for more than seven days, after weekly washing or if it has been dropped.
Rinse their mouth out with water after inhaling the dose to minimise the risk of oropharyngeal thrush. Do not swallow.
On actuation of Budesonide/Glycopyrronium/Formoterol Fumarate (Breztri Aerosphere), a volume of the suspension is expelled from the pressurised container. When the patient inhales through the mouthpiece at the same time as actuating the inhaler, the substance will follow the inspired air into the airways.
Patients who find it difficult to coordinate actuation with inhalation may use Budesonide/Glycopyrronium/Formoterol Fumarate (Breztri Aerosphere) with a spacer to ensure proper administration of the medicinal product. Budesonide/Glycopyrronium/Formoterol Fumarate (Breztri Aerosphere) can be used with spacer devices including the Aerochamber Plus Flow-Vu (see Pharmacology: Pharmacokinetics under Actions).
Incompatibilities: Not applicable.
Special precautions for disposal: Any unused medicinal product or waste material should be disposed of in accordance with local requirements. The pressurised container should not be broken, punctured or burnt, even when apparently empty.